Artificial Intelligence (AI) and Big Data represent two of the most influential technological innovations in modern healthcare. Their application in nursing research goes beyond simple data analysis, offering predictive modeling, real-time clinical decision support, and advanced patient care optimization. Nursing, being the backbone of healthcare delivery, produces vast amounts of structured and unstructured data such as patient records, nurse–patient interactions, monitoring device outputs, and administrative logs. AI algorithms can detect hidden patterns, while Big Data platforms ensure scalability and efficiency in handling millions of records. Together, they provide new opportunities for nursing students, educators, and practitioners to enhance patient safety, reduce workload, and improve evidence-based practice. This study critically explores the roles, benefits, methodologies, and challenges of AI and Big Data in the domain of nursing research, while also presenting examples, calculations, and graphs to illustrate their impact on healthcare outcomes.
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